1. Bruch’s membrane is found in—
(A) Inner ear (B) Uvea of eye (C) Testes (D) Pancreas
2. Which part of brain allows one side of brain to control opposite side of body?
(A) Midbrain (B) Medulla (C) Cerebellum (D) Pons
3. Fetuin is found in—
(A) Foetus (B) Liver (C) Spleen (D) None of these
4. Hensen’s body is associated with—
(A) Retina of eye (B) Organ of Corti (C) Heart (D) Skin
5. Sensory receptor of warmth located principally at the lip of fingers is known as—
(A) Ruffini’s corpuscles (B) Organ of Zuckerkandl (C) Organ of Giraldes
(D) Weber’s organ
6. Which of the following is basic amino acid?
(A) Alanine (B) Aspartic acid (C) Asparagine (D) Arginine
7. Which of the following amino acid is sulphur bearing compound?
(A) Methionine (B) Alanine (C) Aspartic acid (D) Arginine
8. Negri bodies are associated with—
(A) Rabies (B) Typhoid (C) Tuberculosis (D) Hepatitis
9. Schultze’s bundle is associated with—
(A) Brain (B) Spinal cord (C) Heart (D) None of these
10. Schlemm’s canal is present in—
(A) Eye (B) Cochlea (C) Spinal cord (D) Vertebrae
11. Capsule of Tenon is associated with—
(A) Eyeball (B) Brain (C) Skin (D) Kidney
12. Which of the following law is associated with the fact that anterior spinal nerve roots contain only motor fibres and posterior roots only sensory fibers?
(A) Magendie’s law (B) Bell’s law (C) Both (A) and (B) (D) None of these
13. In birds—
(A) Left oviduct and right aortic arch are present
(B) Left oviduct and left aortic arch are present
(C) Right oviduct, left ovary and right aortic arch arc present
(D) Left oviduct, left ovary and right aortic arch are present
14. Ancestral amphibians were tetrapods that evolved during—
(A) Devonian period (B) Carboniferous period (C) Jurassic period (D) Cretaceous period
15. Community health services involves—
(A) Control of communicable diseases (B) School and health education (C) Awareness of clean environment (D) All the above
16. The active rolling over of endodermal and mesodermal cells from the embryo surface into the interior is defined as—
(A) Ingression (B) Involution (C) Epiboly (D) Inversion
17. The wall of heart is made up of—
(A) Epicardium (B) Myocardium (C) Endocardium (D) All the above
18. Genetic counsellors can identify heterozygous individuals by—
(A) Height of individual (B) Colour of individual (C) Screening procedures (D) All the above
19. Which of the following enzyme is secreted by intestinal mucosa that remain closely associated with the microvilli?
(A) Peptidase (B) Disaccharidase (C) Trypsin (D) Both (A) and (B)
20. Which of the following is absorbed by intestinal mucosa by active transport?
(A) Galactose (B) Glucose (C) Fructose (D) Both (A) and (B)
21. A starving person consumes first—
(A) Body fats (B) Body proteins (C) Vitamins (D) Stored glycogen
22. The functional unit of contractile system in striated muscle is—
(A) Cross bridges (B) Sarcomeres (C) Myofibril (D) Z-band
23. Globular proteins undergo structural changes in response to extremes of pH or temperature, is called—
(A) Renaturation (B) Denaturation (C) Combination (D) Both (A) and (B)
24. The study of relationships between size and shape is known as—
(A) Allometry (B) Heterochrony (C) Isometry (D) Allochrony
25. A localised tumour covered by connective tissue is called—
(A) Metastasis (B) Neoplasm (C) Benign tumour (D) Malignant tumour
26. Hurthle cell is associated with—
(A) Thyroid gland (B) Pituitary gland (C) Adrenal gland (D) Pancreas
27. A metastatic cancerous tumour is termed ‘sarcoma’, if the disorder is in—
(A) Immune system (B) Epithelial cells (C) Fibroblasts (D) Circulatory system
28. Graft between isogenic individuals is known as—
(A) Syngraft (B) Allograft (C) Xenograft (D) None of these
29. The most striking example of point mutation is found in a disorder called—
(A) Thalassemia (B) Nightblindness (C) Down’s syndrome (D) Sickle-cell anaemia
30. The phenomenon of ‘industrial melanism’ demonstrates—
(A) Natural selection (B) Induced mutation (C) Reproductive isolation (D) Geographical isolation
31. Overproduction of which of the following neurotransmitter has been associated with the mental disorder ‘Schizophrenia’?
(A) Acetylcholine (B) GABA (C) Dopamine (D) Serotonin
32. Milk tastes sour when kept in the open for sometime due to formation of—
(A) Carbonic acid (B) Lactic acid (C) Citric acid (D) Malic acid
33. Red tide is caused by—
(A) Protozoans (B) Corals (C) Dinoflagellates (D) All the above
34. A type of hypersensitivity to allergen in which humoral antibodies attach to mast cells and basophils, may result in circulatory shock, is called—
(A) Orthopnea (B) Anaphylaxis (C) Rhinitis (D) Immunologic surveillance
35. Organisms with very high intrinsic growth rates have—
(A) Long generation times (B) Short generation times (C) No courtship behaviours (D) No carrying capacity
36. Which of the following organism is iteroparous?
(A) Pacific salmon fish (B) Virus (C) Bacteria (D) Humans
37. A micromutation is—
(A) Polyploidy (B) Addition of chromosome (C) Deletion of chromosome
(D) Change in gene frequency
38. The limited period of sexual receptivity that occurs around the time of ovulation in all female mammals except humans is called—
(A) Menstruation (B) Luteinization (C) Oogenesis (D) Estrus
39. The rate and force of the heart-beat, and the secretion of digestive glands are controlled by-
(A) Central nervous system (B) Spinal nerves (C) Cranial nerves (D) Autonomic nervous system
40. Glycosidic bond is broken during digestion of—
(A) Protein (B) Starch (C) Lipid (D) All the above
41. Postganglionic parasympathetic fibres are—
(A) Adrenergic (B) Cholinergic (C) Both (A) and (B) (D) None of these
42. In glycosuria disorder, urine contains—
(A) Amino acid (B) Inorganic ions (C) Glucose (D) Epithelial cells
43. Mammillary bodies are attached to the ventral side of—
(A) Olfactory lobe (B) Cerebral hemisphere (C) Diencephalon (D) Medulla oblongata
44. Argentaffin cells arc associated with—
(A) Tumour (B) Heart muscle (C) Pericardium (D) Pelvis of kidney
45. Sweating on palm and sole due to psychic stimuli is called—
(A) Bradykinin (B) Blushing (C) Cold sweat (D) None of these
46. Inherited Rh gene is found in—
(A) Rh+ individuals (B) Rh individuals (C) AB blood group individuals
(D) O blood group individuals
47. The ‘soft spot’ on the top of an infant’s skull is called—
(A) Suture (B) Fontanel (C) Ligament (D) Fascia
48. Concentration of carbonic acid does not increase in blood due to the presence of—
(A) Na+ (B) K+ (C) Ca++ (D) Mg++
49. Staph food poisoning is related with—
(A) Salmonella bacteria (B) Clostridium bacteria (C) Staphylococcus bacteria (D) None oft these
50. Capacitation is—
(A) Final stage in maturation of spermatozoa (B) Final stage in fertilization (C) Maturation of ovum (D) All of these
Answers with Hints
1. (B) Bruch’s membrane is a glassy membrane of the uvea of eye lying between the choroid membrane and the pigmented epithelium of the retina. It is also known as lamina basalis of the choroid or vitreous lamella.
2. (B) Medulla contains ascending sensory and descending motor nerves, and contains site where major motor nerves cross to opposite side of nervous system, allowing one side of brain to control opposite side of body.
3. (A) Fetuin is a type of globulin found in foetus and is required for the cell proliferation and growth of foetus.
4. (B) Hensen’s body is modified Golgi net found in the hair cells of the Organ of Corti.
5. (A) Ruffini’s corpuscles are encapsulated sensory nerve endings found in subcutaneous
tissue of finger tips and thought to mediate sense of warmth.
6. (D) Arginine is crystalline basic amino acid obtained from decomposition of vegetable tissues, protamines and proteins.
8. (A) Negri bodies are very minute bodies formed in nerve cells of the brain of one affected by rabies.
9. (B) Schultzc’s bundle is commashaped path of fibres in middle of spinal cord’s fasciculus cuneatus.
10. (A)Schlemm’s canal is space or series of spaces at the junction of the sclera and the cornea of the eye into which aqueous humor is drained from the anterior chamber through
the pectinate villi.
11. (A) Capsule of Tenon is a thin fibrous sac enveloping the eyeball, forming a socket in which it rotates.
12. (C> 13. (B)
14. (B) Carboniferous was the recent period of the Palaeozoic, some 355-280 million years ago. It was characterized by the evolution amphibians on swampy land, a few primitive early reptiles and giant ferns.
16. (B) Involution is rolling over of cells during gastrulation from the surface towards interior
of the developing gastrula.
17. (D) Heart’s wall possesses three layers, i.e., the outer epicardium (serous layer), the middle myocardium (cardiac muscle), and the inner endocardium. Endocardium lines the four chambers of the heart and covers the valves.
18. (C) Carriers of genetic disorders (those heterozygous for the condition, but who do not themselves exhibit it) can be diagnosed through screening procedures during genetic counselling.
19. (D) The epithelial cells of the intestinal mucosa manufacture and secrete peptidase and disaccharidase digestive enzymes. They are not released into the lumen of the intestine but remain closely associated with the villi of the epithelial cells.
20. (D) The glucose and galactose enter intestinal mucosa by active transport, while fructose enters by facilitated diffusion.
21. (D) The liver stores glycogen to fulfill body’s requirement of glucose for energy during starvation.
23. (B) Changes occurring to molecules of globular proteins and nucleic acid in solution in response to extreme s of pH or temperature is called denaturation.
24. (A) Allometry is the study of relationship between size and shape. Organisms do not grow isometrically, rather proportions change as size changes.
26. (A) Hurthle cell is benign or malignant tumour of the thyroid gland. The cells are large and acidophilic.
27. (C) Sarcomas are cancer of connective tissues. Fibroblast is the characteristic cell type of vertebrate connectivc tissue.
28. (A) Syngraft is also known as isograft. It is a kind of grafting between isogenic individuals such as identical twins.
29. (D) Point mutations involve minor changes in the genetic material, often single base-pair substitution. Sickle-cell anaemia is genetically determined disorder, caused by homozygosity, producing a single amino acid substitution in the b-chain of the normal haemoglobin mole-
30. (A) Industrial melanism provides one of the best examples of evolution within species and of natural selection.
31. (C) Dopamine is a neurotransmitter whose low concentration produces symptoms of Parkin-
son’s disease and over production causes Schizophrenia.
32. (B) Lactic acid is a carboxylic acid, formed in metabolism of many bacteria. In milk, lactose is converted into lactic acid by metabolic activities of bacteria. Lactic acid gives sour taste to milk.
33. (C) Red tide is reddish discolouration of coastal surface waters due to concentrations of certain toxin producing dinoflagellates.
34. (B) Anaphylaxis is a type of hypersensitivity resulting due to interaction of humoral antibodies with mast cells and basophils.
35. (B) 36. (D)
37. (D) Mutations which are large and conspicuous are called macromutations and those very inconspicuous are called micromutation. Change in the genie frequency is the constituent of microevolution.
38. (D) Estrus is the cyclic period of sexual activity in non human female mammals, characterized by congestion of and secretion by the uterine mucosa. During estrus the animal is said to be ‘in heat’.
39. (D) 40. (B)
41. (B) Cholinergic fibres include all preganglionic fibres, all postganglionic parasympathetic fibres, which liberate acetylcholine at their nerve endings.
43. (C) A pair of small rounded bodies, the mammillary bodies lie behind the infundi-bulum in Diencephalon.
44. (A) Argentaffinoma is tumour, having argentaffin cells.
45. (C) 46. (A)
47. (B) In a newborn infant, the bones of the skull arc still developing and these are relatively wide spaces between them. The spaces contain tough sheets of connective tissue that connect the bones and are called fontanels.
49. (C) Staph food poisoning, once known as ptomaine poisoning, results from toxins produced by Staphylococcus bacteria growing on food.
50. (A) Capacitation is the final stage in maturation of mammalian spermatozoa, without which they cannot engage in fertilization.