• Grassi (1900) fully described the life-cycle of Plasmodium in the stomach of Anopheles. • Paroxysm results due to sufficient accumulation of haemozoin and other toxins in the human blood. • Tertian malaria is caused by P. vivax. Recurrence of fever is after every 48 hours (every third day). • In benign tertian malaria, there
The characteristic features of the Sporozoite state of Plasmodium are: Sickle shaped (10-14µm in length and 1 µm in breadth) with both ends pointed. Covered by two membranes, the inner one is rigid while the outer one is wavy. Apical part constitutes the apical complex. Nucleus situated in the micropyle present in the broad central
Plasmodium gets transmitted into human body in the Sporozoite state. During the blood meal, female Anopheles mosquito transmits the parasite to healthy human body along with saliva. The parasite was, however, collected from infected man while blood-feeding infection is caused by several spindle shaped sporozoites.